حنان سيد محمد ابوزيد

استاذ مساعد - امين مجلس قسم الروماتيزم والتاهيل

كلية الطب

العنوان: Sohag University- Faculty of Medicine- Rheumatology and Rehabilitation department


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2018 | الكلمات المفتاحية SSc, Atherosclerosis,
Study of the osteoprotegerin/receptor activator of nuclear factor-kB ligand system association with inflammation and atherosclerosis in systemic sclerosis
Objective: we aimed to study systemic sclerosis patients in order to assess osteoprotegerin/Receptor activator of nuclear factor-kB ligand (OPG/RANKL) system and find the relation of these biomarkers with the clinical features of the disease, the carotid intima thickness, markers of inflammation, lipid profile, and other laboratory characteristics. Methods: both the level of (RANKL), (OPG) in sera of participants, in 30 ... إقراء المزيد

2018 | الكلمات المفتاحية Cervical affection, RA,
Is It the Age at Disease Onset or the Disease Radiological Severity That Affects Cervical Spine Involvement in Patients With Rheumatoid Arthritis?
Bac kgro und: Cervical spine involvement in patients with rheumatoid arthritis (RA) can cause pain and disability, with a variety of neurologic signs and symptoms. Objecti ves: To investigate the relationship between structural cervical spine involvement in patients with RA with the age at disease onset and the degree of radiologic severity of RA measured by Larsen scoring. Pati ents ... إقراء المزيد

2017 | الكلمات المفتاحية UCLA, GIT, SSc,
High-resolutionmanometrycomparedwiththeUniversityof California, LosAngelesSclerodermaClinicalTrialsConsortium GIT 2.0inSystemicSclerosis
Objectives: Tostudyesophagealhighresolutionmanometry(HRM)insystemicsclerosis(SSc)patients and thecorrelationof findings toTheUniversityofCalifornia,LosAngelesSclerodermaClinicalTrials Consortiumgastrointestinaltract2.0(UCLASCTC_GIT2.0). Methods: FortySScpatientswereadministeredtotheUCLASCTCGIT2.0.PatientsunderwentHRMstudy (Solar GIMMS).HRMdatawerecomparedwith15healthyvolunteers. Results: Forty patientswithmeanage46 7 7 yearsanddiseaseduration9.3 7 7 yearsreportedupper (85.7%),lowerGIsymptoms(75%),while5%reportednosymptoms.Mean 7 SD scoresofUCLA SCTC_GIT2.0itemswereasfollows:reflux 1.2 7 0.8, distention1.6 7 1.2,fecalsoiling0.3 7 0.9, diarrhea 0.8 7 1,social1 7 1,emotional1 7 1.1,constipation0.5 7 0.9, andtotalGITscore0.9 7 0.6. Lower esophagealsphincter(LES)pressureanddistalesophagealamplitudeweresignificantly lowerin SSc patientsthancontrols.Mainmanometric findings weredecreasedLESrestingpressure(40%)and aperistalsis(40%).RegressionanalysesshoweddistalesophagealamplitudeandLESrestingpressure negativelycorrelatedwithreflux score(r ¼ −0.64; p ¼ ... إقراء المزيد

2015 | الكلمات المفتاحية GIT, SSc,
GIT manifestations of systemic         sclerosis as the most frequent. is it the most irritant too?
Gastrointestinal involvement (GI) in systemic sclerosis (SSc) is one of the most frequent symptoms in SSc and include a wide range of symptoms from gastro-oesophageal reflux to faecal incontinence. These have a negative impact on patient quality of life. The SSc_GIT 1.0 is a disease-specific HRQOL instrument for patients with SSc to assess their GIT-related activity and severity, High-resolution manometry ... إقراء المزيد

2015 | الكلمات المفتاحية AS, SLE, RA, Vit D,
). Hypo-vitaminosis D in Patients with Rheumatoid Arthritis, Systemic Lupus Erythematosus and Ankylosing Spondylitis
Hypo-vitaminosis D and its relevance to the stability of the immune system represent an interesting investigational topic in the field of rheumatology. Objectives: survey hypo-vitaminosis D and its relation to disease activity parameters in a population of patients with autoimmune diseases. Materials and methods: case control study including 70 patients: 30 patients with rheumatoid arthritis (RA), 30 patients with systemic ... إقراء المزيد

2014 | الكلمات المفتاحية IL18, SLE, SLEDAI,
Serum interleukin-18 and interleukin-10 levels in systemic lupus erythematosus: correlation with SLEDAI score and disease activity parameters
Aim The aim of the study was to assess serum levels of interleukin (IL)-18 and IL-10 in systemic lupus erythematosus (SLE) patients and their relationship with disease activity. Patients and methods Thirty patients with SLE and 20 healthy controls were investigated in this study. The serum IL-18 and IL-10 levels were determined using enzyme-linked immunosorbent assay and their correlations with ... إقراء المزيد

2013 | الكلمات المفتاحية Early RA, IL17,
Enhanced and persistent levels of IL‐17+ CD4+ T cells and serum IL‐17 in patients with early inflammatory arthritis
Summary Prognosis of patients with early inflammatory arthritis (EIA) is highly variable. The aim of this study was to compare, longitudinally and crosssectionally, the levels of cytokine-expressing cells in peripheral blood (PB) from patients with EIA to those in established rheumatoid arthritis (RA) and healthy controls (HC). PB mononuclear cells from HC (n = 30), patients with EIA (n = ... إقراء المزيد

2013 | الكلمات المفتاحية MCV, Rheumatoid,
Diagnostic Value of Antibodies Against a Modified Citrullinated Vimentin in Egyptian Patients with Rheumatoid Arthritis
Abstract Objective: To explore the sensitivity and specificity of sero-positivity to antibodies against modified citrullinated vimentin antibodies (anti-MCV) in comparison with anti-CCP2-in rheumatoid arthritis (RA) among Egyptians, considering the possible correlation to demographic and disease related features in the study group. Patients and methods: The study included forty patients with rheumatoid arthritis (RA). Patients assessment measures involved the disease activity ... إقراء المزيد

2012 | الكلمات المفتاحية Rheumatoid, cytokines,
CONVENTIONAL THERAPY FOR EARLY INFLAMMATORY ARTHRITIS DOES NOT MODIFY PERIPHERAL BLOOD CYTOKINE PROFILES Nicola J Gullick, David M Jayaraj, Hanan S Abozaid, Hayley G Evans, David L Scott, Ernest Choy, Leonie S Taams BACKGROUND: Many patients with early inflammatory arthritis (EIA) have inadequate responses to initial therapy, even if combination DMARDs and steroids are used at an early stage. We ... إقراء المزيد

2010 | الكلمات المفتاحية Rheumatoid, ethnicity,
ETHNICITY AND RHEUMATOID ARTHRITIS: A SYSTEMATIC REVIEW Hanan S Abozaid1, 2, Nihal A. Fathi2, David L Scott1, Sophia Steer1 * Academic Rheumatology, King’s college London, London SE5 9RJ, UK * Rheumatology department, Sohag university, Egypt BACKGROUND Several patient-related factors impact on the clinical phenotype and outcome of rheumatoid arthritis (RA). The effects of gender and deprivation are well known. The ... إقراء المزيد

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