Prof. Ahmed Mohamed Abu-Dief

Professor - Professor of Physical and Inorganic Chemistry

Faculty of science

Address: Behind hospital of Sohag University - Ali Ebn Abi Taleb Street



Publications Which contain the keyword: cancer

جيناتك ليست قدرك. Genes and the Environment: The Science of Epigenetics
At one time scientists believed that our DNA carry the key to preventing and reversing disease, but now we know that the environment and not our genes is the primary triggering of health and longevity. The science of epigenetics is explaning what we’ve long think about our biological destiny upside/ down. Although it remains that our DNA and our genetic ... Read more

2018-10-22 20:09:15 Keywords cholesteatoma, staging, Immunohistochemistry, cancer,
SOM CLEFT Scoring/Staging System for Tympanomastoid Cholesteatoma
_OBJECTIVES_: To adopt a newly designed scoring/staging system for of tympanomastoid cholesteatoma similar to cancer staging protocols. _METHODS_: Our system relied on clinical, CT findings, and confirmed with intraoperative findings. All bony items that could be affected by cholesteatoma were scored, including: scutum (S), ossicles (O), mastoid (M), posterior canal wall (C), lateral sinus plate (L), inner ear (E), facial ... Read more

2018-10-13 06:06:02 Keywords resection, cancer, non-small cell, Metastasis,
Incidence of silent brain metastasis in patients with non-small cell lung cancer
BACKGROUND: Brain is one of the common sites of metastasis in . patients with lung cancer.This is more likely to be present in cases with small cell lung cancer SCLC than those with non-small cell lung cancer NSCLC OBJECTIVE: To estimate the incidence of silent brain metastasis in patients with NSCLC clinically stages II,III and IV at presentation :PATIENTS AND ... Read more

2018-10-14 17:54:44 Keywords Mitochondrial function, cancer, melatonin,
Oncostatic effect of melatonin in head and neck cancer: role of mitochondrial function
Cancer cells have some special features that give them the ability to change and to resist different types of treatments. These changes are produced by modifications in the mitochondrial bioenergetics, that is, a switch in the metabolism. These advantages consist in the so-called Warburg effect. Cancer cells depend on glycolysis instead of oxidative phosphorylation to get the energy necessary to ... Read more

2018-10-05 17:34:27 Keywords Monoclonal, cancer, Therapy,
Monoclonal antibodies in cancer detection and therapy
Monoclonal antibodies in cancer detection and therapy .essay in clinical application of Monoclonal antibodies in cancer detection and therpy The development of monoclonal antibodied have already improvedthe outcome for cancer patients Read more

2018-09-28 11:22:49 Keywords cancer, polyps, Peutz Jegher,
Peutz Jegher hamartomatous polyps: How it progress to cancer?
ABSTRACT: Peutz-Jegher Syndrome (PJS) is an autosomal dominant inherited disease, characterized by gastrointestinal (GI) hamartomatous polyps frequently associated with GI and non-GI tumors, leading to reassessment of cancer risk in this lesion. Another type of hamartomatous polyps, the hyperplastic polyps, is common in the colon and in its pure form carries no risk of malignancy, whereas adenomas of the colon ... Read more

2018-09-22 20:55:30 Keywords cancer,
arburg effect increases steady-state ROS condition in cancer cells through decreasing their antioxidant capacities (anticancer effects of 3-bromopyruvate through antagonizing Warburg effect).
Cancer cells undergo an increased steady-state ROS condition compared to normal cells. Among the major metabolic differences between cancer cells and normal cells is the dependence of cancer cells on glycolysis as a major source of energy even in the presence of oxygen (Warburg effect). In Warburg effect, glucose is catabolized to lactate that is extruded through monocarboxylate transporters to ... Read more

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